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B
vitamines tegen darmkanker.
Vrouwen
die extra B vitamines i.h.b. B6 tot zich nemen hebben een fors mindere kans op
darmkanker. als ze ook nog eens een glaasje alcohol daarbij drinken kan die kans
oplopen tot 70%. Vrouwen die niet voldoende vitamine B6 innemen en toch dat
glaasje of zelfs meer drinken hebben daarentegen een verhoogd risico op
darmkanker. Althans volgens een studie onder 67.000 vrouwen in de leeftijd van
40 tot 75 jaar. Vitamine B6 zit in aardappels, granen, bonen, vlees, gevogelte,
fruit en groenten. Bij goede voedingsgewoontes zal de hoeveelheid B6 voldoende
zijn, doch bij een glaasje extra zal ook extra inname moeten zijn van vitamine
B6 om de kans op darmkanker sterk te kunnen verkleinen.
Increased
Vitamin B Consumption Reduces Women's Risk Of Colorectal Cancer
--
According to a study published in the American Gastroenterological Association (AGA)
journal Gastroenterology, women with a high dietary intake of vitamin B6
over several years have a decreased risk of colorectal cancer (CRC). Women who
consume moderate to large amounts of alcohol in addition to vitamin B6 have more
than a 70 percent reduced risk of developing CRC.
"Consuming
a diet high in vitamin B6 may reduce the risk of colorectal cancer in women,
more specifically those who consume alcohol," said Susanna Larsson, MSc,
study author with the Karolinska Institutet. "Inadequate vitamin B6 status
may lead to the development of cancerous polyps in the colon, so it is important
for women to maintain a normal to high intake of vitamin B6."
The
second-leading cause of cancer deaths in the United States, it is estimated that
more than 28,000 women with CRC will die in 2005. While increased vitamin B6
consumption decreases the risk of colorectal cancer, it does not eliminate the
need for regular screening. Guidelines of multiple agencies and professional
societies underscore the importance of colorectal cancer screening for all
individuals 50 years of age and older.
Researchers
at the Karolinska Institutet in Stockholm, Sweden and the Harvard School of
Public Health used data from the Swedish Mammography Cohort to evaluate the
association between long-term dietary vitamin B6 intake from food sources and
colorectal cancer risk, and its modification by alcohol consumption. Nearly
67,000 women, aged 40 to 75 years, responded to a questionnaire that solicited
data on diet, family history of CRC and use of dietary supplements. Researchers
observed that alcohol consumption in women with low vitamin B6 intake resulted
in higher risk of developing colorectal cancer and that increasing intake
reduces this risk significantly.
The
recommended daily dietary intake of vitamin B6 for non-pregnant women in the
United States is 1.3 to 1.5 mg. Vitamin B6 is found in a wide variety of foods,
including fortified cereals, beans, meat, poultry, fish, and some fruits and
vegetables. It performs a wide variety of functions in the body, including
helping to maintain normal blood glucose levels, fighting off infections and
creating hemoglobin to ensure that oxygen gets to important organs and tissues.
While
the study shows that consuming high amounts of vitamin B6 reduces the risk of
colorectal cancer in women who drink, researchers say findings need further
confirmation in large prospective cohort or intervention studies.
"These
findings may have important implications for the prevention of colorectal cancer
in women who consume alcohol because their vitamin B6 status can be easily
improved through dietary modifications, vitamin supplementation and
fortification," said Larsson.
About
the Study
Researchers
from the Harvard School of Public Health and the Karolinska Institutet in
Stockholm, Sweden conducted a population-based study using the Swedish
Mammography Cohort, a study established between 1987 and 1990 that takes into
account information on diet, educational level, weight and height of 66,651
women aged 40 to 75 years living in two central Swedish counties. Researchers
sought to evaluate the association between long-term dietary vitamin B-intake
and colorectal cancer risk, and its modification by alcohol consumption in this
cohort of women. (Juni 2005)