Lignanen
in de voeding tegen borstkanker.*
Uit een Franse studie onder ruim 58.000 postmenopauzale voruwen blijkt dat het regelmatig eten van voeding met lignanen de kans op hormoongevoelige borstkanker met 17% doet verminderen. Lignanen behoren tot de familie van fyto-oestrogenen die ruim aanwezig zijn in o.a. lijnzaad en volkoren granen.
Plant
Compound In Diet Associated With Decreased Risk Of Postmenopausal Breast Cancer
Postmenopausal
women whose diet contains high amounts of lignans, estrogen-like chemical
compounds found in plants, may have a reduced risk of breast cancer.
Lignans, which are found in flaxseed and a variety of fruits, vegetables and
whole grains, belong to a family of compounds called phytoestrogens. Because of
their hormone-like properties, phytoestrogens can bind to estrogen receptors,
and some have suggested they may play a role in preventing breast cancer.
Studies of Asian populations have found that women whose diets contain many
foods made of soy, which are rich in another type of phytoestrogen, have a lower
breast cancer risk.
Marina Touillaud, Ph.D. of the National Institute of Health and Medical Research
in France, and colleagues administered a diet history questionnaire to 58,049
postmenopausal French women to examine the association between the consumption
of four types of plant lignans and the risk of invasive breast cancer.
After a median follow-up of 7.7 years, 1,469 of the women were diagnosed with
breast cancer. Among women with the highest total lignan intake, there were 376
cases of breast cancer per 100,000 person-years compared with 411 cases among
women with the lowest intake - corresponding to a 17 percent relative decrease
in the risk of breast cancer. The association was limited to breast cancers
positive for estrogen and progesterone receptors.
"Although the possible role of plant foods in breast cancer prevention is
still debated, increasing dietary lignan intake may be an interesting potential
preventative approach. In view of the epidemiologic results of this study, the
recommendation that women should consume diets that consist largely of fruits,
vegetables, and cereals - all foods rich in lignans - should continue," the
authors write.
Contact: Dr.Francoise Clavel-Chapelon, National Institute of Health and Medical
Research (April 2007) (Opm.
Meer over lignanen)