Transvetten en vruchtbaarheid.*

Uit een onderzoek onder ruim 18.000 vrouwen blijkt dat transvetten de kans op vruchtbaarheidsproblemen bij vrouwen flink doen toenemen. Vrouwen, waarvan 2% van hun dagelijkse calorieën uit transvetten bestaat, hebben 70-100% meer kans op vruchtbaarheidsproblemen als gevolg van het uitblijven van een ovulatie. Bij een gemiddeld dagelijks inname van 2.000 cal. betekent dat 4 gram transvetten per dag al voor problemen kan zorgen. 4 gram transvet kan men al binnen krijgen met het eten van 1 donut of 1 portie patat frites. Volgens de onderzoeksleider Jorge Chavarro blijkt dat zelfs al kleine hoeveelheden transvetten duidelijke gevolgen kunnen hebben voor de vruchtbaarheid.

Dietary fatty acid intakes and the risk of ovulatory infertility 1,2,3

Jorge E Chavarro, Janet W Rich-Edwards, Bernard A Rosner and Walter C Willett

1 From the Departments of Nutrition (JEC and WCW), Epidemiology (JEC, JWR-E, and WCW), and Biostatistics (BAR), Harvard School of Public Health, Boston, MA; and the Department of Ambulatory Care and Prevention (JWR-E) and the Channing Laboratory, Department of Medicine, Brigham and Women's Hospital (JWR-E, BAR, and WCW), Harvard Medical School, Boston, MA

Background:Pharmacologic activation of the peroxisome proliferator–activated receptor gamma improves ovulatory function in women with polycystic ovary syndrome, and specific dietary fatty acids can affect PPAR-gamma activity.

Objective:The objective of the study was to assess whether the intakes of total fat, cholesterol, and major types of fatty acids affect the risk of ovulatory infertility.

Design:We conducted a prospective cohort study of 18 555 married, premenopausal women without a history of infertility who attempted a pregnancy or became pregnant between 1991 and 1999. Diet was assessed twice during follow-up by using a food-frequency questionnaire.

Results:During follow-up, 438 incidents of ovulatory infertility were reported. In logistic regression analyses, intakes of total fat, cholesterol, and most types of fatty acids were not related to ovulatory infertility. Each 2% increase in the intake of energy from trans unsaturated fats, as opposed to that from carbohydrates, was associated with a 73% greater risk of ovulatory infertility after adjustment for known and suspected risk factors for this condition [relative risk (RR) = 1.73; 95% CI: 1.09, 2.73]. Obtaining 2% of energy intake from trans fats rather than from n–6 polyunsaturated fats was associated with a similar increase in the risk of ovulatory infertility (RR = 1.79; 95% CI: 1.11, 2.89). In addition, obtaining 2% of energy from trans fats rather than from monounsaturated fats was associated with a more than doubled risk of ovulatory infertility (RR = 2.31; 95% CI: 1.09, 4.87).

Conclusion:trans Unsaturated fats may increase the risk of ovulatory infertility when consumed instead of carbohydrates or unsaturated fats commonly found in nonhydrogenated vegetable oils. (Jan. 2007) (Opm. Meer over transvetten)  

 

 

 

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